Epi Genesys Limited Apps

SampSize is an application to assist in thedesign of clinical trials by calculating the sample size usinginputs provided by the user.Features calculations for:- Normal and binary endpoints- Parallel and crossover designs- Superiority, Non-Inferiority, Equivalence, Bio-equivalence andPrecision objectivesSampSize calculates either the required sample size for adesired power, or calculates the power of a trial for a givensample size. It allows users to specify inputs such as significancelevel, power, mean difference (or limit), standard deviation, andthe allocation ratio.Developed in collaboration with Dr Steven A Julious, MedicalStatistics Group, School of Health and Related Research, TheUniversity of Sheffield, UK.References:- Julious, SA. Sample sizes for clinical trails. Chapman andHall, 2009.- Julious, S. J. (2004). Tutorial in Biostatistics: Sample sizesfor clinical trials with Normal Data. Statistics in Medicine, 23,1921-86.- Julious, S. A. & Campbell, M. J. (2012). Tutorial inbiostatistics: sample sizes for parallel group clinical trials withbinary data. Statistics in Medicine, doi:10.1002/sim.5381.- Julious SA & Owen R. Sample size calculations fornon-inferiority studies with binary outcomes. Statistical Methodsin Medical Research (DOI: 10.1177/0962280210378945).- Julious SA. An introduction to statistics in early phasetrials. Wiley, 2010.